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Work Under Way

Question

What is the relationship between specific nutrients from supplements and/or fortified foods consumed during infancy and toddlerhood and bone health? 

Approach to Answering the Question
Update to Existing NESR Systematic Review

Subcommittee
Birth to 24 Months Subcommittee

Systematic Review Protocol
Developed for each scientific question being examined, the protocol describes the plan for how the systematic review was conducted. The protocol provides the: 

  • Analytic framework, 
  • Literature search and screening plan, and 
  • Literature search and screening results. 

See the full protocol for the question, what is the relationship between specific nutrients from supplements and/or fortified foods consumed during infancy and toddlerhood and bone health? 

View Full Protocol

Draft Conclusion Statement

The draft conclusion statements listed below describe the state of the science related to the specific question examined. Draft conclusions are not considered final until they have been deliberated with and decided upon by the full Committee and published in the Committee’s final advisory report. Individual conclusion statements should not be interpreted as dietary guidance or the Committee’s overarching advice to the Departments. 

Vitamin D

Limited evidence suggests that there is no relationship between consumption of 400 IU per day of vitamin D from supplements under 12 months of age, compared with higher dosages of up to 1600 IU per day, and biomarkers of bone metabolism followed up to 36 months of age. Grade: Limited

Insufficient evidence is available to determine the relationship between 400 IU per day of vitamin D from supplements, compared with higher dosages, and bone mass, rickets, or fracture. Grade: Grade Not Assignable

Insufficient evidence is available to determine the relationship between 400 IU per day of vitamin D from supplements, compared with lower dosages, and bone mass, biomarkers of bone metabolism, rickets, or fracture. Grade: Grade Not Assignable

Insufficient evidence is available to determine the relationship between vitamin D from supplements, compared with no vitamin D from supplements, and bone mass, biomarkers of bone metabolism, rickets, or fracture. Grade: Grade Not Assignable

Insufficient evidence is available to determine the relationship between vitamin D from supplements, compared with vitamin D from fortified foods, and bone mass, biomarkers of bone metabolism, rickets, or fracture. Grade: Grade Not Assignable