What is the relationship between vitamin B12 from supplements and/or fortified foods consumed before and during pregnancy and lactation and specific health outcomes?
Approach to Answering the Question
NESR Systematic Review
Pregnancy and Lactation Subcommittee
Systematic Review Protocol
Developed for each scientific question being examined, the protocol describes the plan for how the systematic review will be conducted. The protocol provides the:
- Analytic framework,
- Literature search and screening plan, and
- Literature search and screening results.
For this question, dietary supplement is defined as a product (other than tobacco) that: is intended to supplement the diet; contains one or more dietary ingredients (including vitamins; minerals; herbs or other botanicals; amino acids; and other substances) or their constituents; is intended to be taken by mouth as a pill, capsule, tablet, or liquid; and is labeled on the front panel as being a dietary supplement. Fortification is defined as the deliberate addition of one or more essential nutrients to a food, whether or not it is normally contained in the food. In addition, the specific outcomes include micronutrient status, risk of gestational diabetes, hypertensive disorders during pregnancy, human milk composition, and developmental milestones, including neurocognitive development.
This page will be updated with the draft conclusion once it has been developed. Draft conclusions are not considered final until they have been deliberated with and decided upon by the full Committee and published in the Committee’s report.