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Work Under Way

Question

What is the relationship between omega-3 fatty acids from supplements before and during pregnancy and lactation and infant developmental milestones, including neurocognitive development?

Approach to Answering the Question
NESR Systematic Review

Subcommittee
Pregnancy and Lactation Subcommittee

Systematic Review Protocol
Developed for each scientific question being examined, the protocol describes the plan for how the systematic review was conducted. The protocol provides the:

  • Analytic framework,
  • Literature search and screening plan, and
  • Literature search and screening results.

See the full protocol for the question, What is the relationship between omega-3 fatty acids from supplements and/or fortified foods consumed before and during pregnancy and lactation and specific health outcomes? 

View Full Protocol

Draft Conclusion Statement

The draft conclusion statements listed below describe the state of the science related to the specific question examined. Draft conclusions are not considered final until they have been deliberated with and decided upon by the full Committee and published in the Committee’s final advisory report. Individual conclusion statements should not be interpreted as dietary guidance or the Committee’s overarching advice to the Departments.

Pregnancy

Limited evidence suggests that omega-3 fatty acid supplementation during pregnancy may result in favorable cognitive development in the child. Grade: Limited

Insufficient evidence is available to determine the relationship between omega-3 fatty acid supplementation during both pregnancy and lactation, or during pregnancy alone, and language and social emotional development in the child. Grade: Grade Not Assignable

Insufficient evidence is available to determine the relationship between omega-3 fatty acid supplementation during pregnancy alone and motor and visual development, academic performance, and the risk of attention-deficit disorder (ADD), attention-deficit/hyperactivity disorder (ADHD), and autism spectrum disorder in the child. Grade: Grade Not Assignable

No evidence is available to determine the relationship between omega-3 fatty acid supplementation during both pregnancy and lactation, or during pregnancy alone, and anxiety or depression in the child. Grade: Grade Not Assignable

Insufficient evidence is available to determine the relationship between omega-3 fatty acid supplementation during both pregnancy and lactation and cognitive development in the child. Grade: Grade Not Assignable

No evidence is available to determine the relationship between omega-3 fatty acid supplementation during both pregnancy and lactation and visual development, academic performance, or the risk of attention-deficit disorder (ADD), attention-deficit/hyperactivity disorder (ADHD), or autism spectrum disorder in the child. Grade: Grade Not Assignable

Lactation

Insufficient evidence is available to determine the relationship between omega-3 fatty acid supplements consumed during lactation alone, and cognitive, language, motor, and visual development in the child. Grade: Grade Not Assignable

Insufficient evidence is available to determine the relationship between omega-3 fatty acid supplements consumed during both pregnancy and lactation or during lactation alone, and cognitive, language, motor, and visual development in the child. Grade: Grade Not Assignable

No evidence is available to determine the relationship between omega-3 fatty acid supplements consumed during both pregnancy and lactation or during lactation alone and academic performance, anxiety, depression, or the risk of attention-deficit disorder (ADD), attention-deficit/hyperactivity disorder (ADHD), or autism spectrum disorder in the child. Grade: Grade Not Assignable

No evidence is available to determine the relationship between omega-3 fatty acid supplements consumed during lactation alone and social-emotional development in the child. Grade: Grade Not Assignable