What is the relationship between alcohol consumption and all-cause mortality?
Approach to Answering the Question
NESR Systematic Review
Beverages and Added Sugars Subcommittee
Existing Systematic Review Protocol
Developed for each scientific question being examined, the protocol describes the plan for how the systematic review was conducted. The protocol provides the:
- Analytic framework,
- Literature search and screening plan, and
- Literature search and screening results.
Draft Conclusion Statement
The draft conclusion statements listed below describe the state of the science related to the specific question examined. Draft conclusions are not considered final until they have been deliberated with and decided upon by the full Committee and published in the Committee’s final advisory report. Individual conclusion statements should not be interpreted as dietary guidance or the Committee’s overarching advice to the Departments.
Primary comparison (among those who drink)
Moderate evidence indicates that higher average alcohol consumption is associated with an increased risk of all-cause mortality compared with lower average alcohol consumption among those who drink. Grade: Moderate
Moderate evidence indicates that binge drinking (consuming 5 or more drinks for men or 4 or more drinks for women during a drinking occasion) is associated with increased risk of mortality, and that more frequent binge drinking is associated with increased mortality risk compared with less frequent or no binge drinking among those who drink. Grade: Moderate
Secondary comparison (between those who currently drink alcohol and those who have never consumed alcohol)
Limited evidence suggests that low average alcohol consumption, particularly without binge drinking, is associated with a lower risk of mortality compared with never drinking. However, in light of the many scientific and public health issues associated with alcoholic beverages, any conclusions about low average consumption compared to those who never drink require careful consideration. Grade: Limited